Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860842 | Toxicology Letters | 2011 | 8 Pages |
Abstract
⺠Effects of neonatal exposure of fluoxetine on subplate neurons are examined. ⺠The coherent growth of structure and function is disrupted by early Flx treatment. ⺠The rheobase for generating action potential is increased in Flx-exposed rats. ⺠Dendritic remodeling of SPns is affected by early Flx treatment. ⺠Numerous short branches are left in SPns of Flx-rats.
Keywords
ABCSubplate neuronTCASPNFLXaCSFphosphate bufferafterhyperpolarizationexcitabilityTime constantEmbryonicTauDendriteRheobaseDevelopmentpostnatal dayRINAntidepressantAHPFluoxetineartificial cerebrospinal fluidinput resistanceSelective serotonin reuptake inhibitorSSRIaction potentialresting membrane potentialPerinatalavidin–biotin complex
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Chun-Chieh Liao, Li-Jen Lee,