Article ID Journal Published Year Pages File Type
5860859 Toxicology Letters 2011 10 Pages PDF
Abstract
► We define the effect of NaAsO2 in early stages of cellular development. ► NaAsO2, in short-term downregulates PDI, PTPRF, HSP90 and VCP, affecting cellular growth or apoptosis. ► NaAsO2, in long-term upregulates B23/nucleophosmin, GRP78, ULK3, TLR6 and MAP3K7. ► Long-term NaAsO2 mainly affects the apoptotic and inflammatory pathways. ► Moreover, we find the non-lethal toxic stresses in NCCIT cells and EBs.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Authors
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