Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860881 | Toxicology Letters | 2011 | 10 Pages |
Abstract
⺠Zinc pyrithione (ZnPyr) is cytotoxic in human dermal fibroblasts. ⺠High ZnPyr induces p53- and p38-dependent response and mitochondrial apoptosis. ⺠Low ZnPyr induces weak stress response without affecting mitogenic signaling. ⺠Low ZnPyr stimulates premature senescence in dermal fibroblasts.
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Authors
Emil Rudolf, Miroslav Cervinka,