Article ID Journal Published Year Pages File Type
5860881 Toxicology Letters 2011 10 Pages PDF
Abstract
► Zinc pyrithione (ZnPyr) is cytotoxic in human dermal fibroblasts. ► High ZnPyr induces p53- and p38-dependent response and mitochondrial apoptosis. ► Low ZnPyr induces weak stress response without affecting mitogenic signaling. ► Low ZnPyr stimulates premature senescence in dermal fibroblasts.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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