Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5861298 | Toxicology in Vitro | 2015 | 28 Pages |
Abstract
The obtained data suggest that an in vitro ITS based on the information obtained from BBB studies and combined with metabolomics, proteomics and neuronal electrical activity measurements performed in stable in vitro neuronal cell culture systems, has high potential to improve current in vitro drug-induced neurotoxicity evaluation.
Keywords
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Authors
Luise Schultz, Marie-Gabrielle Zurich, Maxime Culot, Anaelle da Costa, Christophe Landry, Patricia Bellwon, Theresa Kristl, Katrin Hörmann, Silke Ruzek, Stephan Aiche, Knut Reinert, Chris Bielow, Fabien Gosselet, Romeo Cecchelli, Christian G. Huber,