| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5861412 | Toxicology in Vitro | 2015 | 9 Pages |
Abstract
CuO NPs did not induce any mitochondrial damage up to 6Â h of exposure. No acellular ROS was induced by the CuO NPs, and the levels of intracellular ROS and DNA damage were limited after 2Â h exposure. Necrosis was the main type of cell death observed after 18Â h exposure to CuO NP and dissolved copper.
Keywords
tetramethyl rhodamine methyl ester2′,7′-Dichlorofluorescein-diacetateTMRMFPGRPMIDCFH-DAAASCuOSBSFBSDMEMDLSPBSPCCsROSMitochondrial damageTemALSOxidative stressDulbecco’s Minimal Essential Mediumalkali-labile sitesfetal bovine serumCytotoxicityStrand breaksAtomic absorption spectroscopyinhibitory concentrationconfidence intervalPhosphatidylserinephosphate buffer solutionTransmission electron microscopyNanoparticleNanoparticlesDynamic Light ScatteringPropidium iodideReactive oxygen species
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Ylva Rodhe, Sara Skoglund, Inger Odnevall Wallinder, Zuzana Potácová, Lennart Möller,