| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5861738 | Toxicology in Vitro | 2013 | 9 Pages |
Abstract
- H2O2 treatment reduced neurite outgrowth in differentiated SH-SY5Y cells time-dependently.
- H2O2 modulated autophagic factors including LC3B, Atg7, and Atg12.
- H2O2 increased apoptotic factors including Bax/Bcl-2 ratio, caspase-3, and PARP.
- Inhibition of autophagy by 3MA increased Aβ levels in human neuroblastoma cells exposed to H2O2.
Keywords
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Authors
Ghorbangol Ashabi, Abolhassan Ahmadiani, Azadeh Abdi, Shahnaz Babaei Abraki, Fariba Khodagholi,