Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5861953 | Toxicology in Vitro | 2013 | 13 Pages |
Abstract
⺠Both apoptosis and autophagy were involved in PpIX-SDT induced cytotoxicity of murine leukemia L1210 cells. ⺠Following SDT, autophagy occurred earlier than apoptosis. ⺠Autophagy inhibitors enhanced SDT induced cell apoptosis and necrosis in L1210 cells. ⺠ROS play important role in initiating cell autophagic and apoptotic responses.
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Authors
Xiaobing Wang, Pan Wang, Kun Zhang, Xiaomin Su, Jie Hou, Quanhong Liu,