| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5861956 | Toxicology in Vitro | 2013 | 10 Pages |
Abstract
⺠Cationic nanoparticles reduce TNF-α stimulated IL-8 signaling. ⺠The reductive effects are not caused by ROS production and cytotoxicity. ⺠These particles do not rely on the actin cytoskeleton to reduce signaling. ⺠They require membrane cholesterols to disrupt cellular signaling. ⺠The particles disrupt cellular signaling by inhibiting NF-κB translocation.
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Authors
Chia T. Thach, Jacob N. Finkelstein,