| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862090 | Toxicology in Vitro | 2012 | 8 Pages |
Abstract
⺠Proadifen has anti-proliferative and pro-apoptotic activity in HT-29 cancer cells. ⺠NAG-1 gene silencing by siRNA had no effect on the pro-apoptotic action of proadifen. ⺠GSK-3β plays a significant role in the pro-apoptotic action of proadifen.
Keywords
nonyl phenoxypolyethoxylethanolATF3EGR-1Bcl-xLPARPinduced myeloid leukemia cell differentiation proteinRIPAGSK-3βTRISHT-29Tween 20Bcl-2Mcl-1NP-40TBS(3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide)PBSMCC-555SDSKLF4p53NAG-1FITCHEPESPVDFNSAIDS4-(2-hydroxyethyl)-1-piperazineethanesulfonic acidDMSOMTTSmall interfering RNAsiRNASp-1standard deviationradioimmunoprecipitation assay bufferBaxanalysis of varianceANOVATris(hydroxymethyl)aminomethaneTris buffered salineApoptosisNon-steroidal anti-inflammatory drugsRoom temperaturepolyvinylidene difluorideDimethyl sulfoxidesodium dodecyl sulfateSodium deoxycholateColon cancer cellsPhosphate buffered salineactivating transcription factor 3fluorescein isothiocyanateB-cell lymphoma 2B-cell lymphoma-extra largeSpecificity protein 1Proadifenprotein 53Bcl-2-associated X proteinearly growth response protein 1Propidium iodidepoly (ADP-ribose) polymerase
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Authors
Rastislav Jendželovský, Ján Kovaľ, JaromÃr MikeÅ¡, Zuzana PapÄová, Jana PlÅ¡Ãková, Peter FedoroÄko,