| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862103 | Toxicology in Vitro | 2012 | 6 Pages |
Abstract
⺠CTN dose-dependently reduce secreted testosterone in primary culture Leydig cell. ⺠PS changes and nuclei fragmentation after cell exposure to CTN were indicators of apoptosis. ⺠CTN caused a dose-dependent increase in p53, caspase-9, and caspase-3 expression. ⺠CTN decreased P450scc, 3β-HSD-1 and StAR expressions in Leydig cells.
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Authors
Shuqiang Liu, Dan Wang, Junwen Zhang, Dongzhi Zhang, Meng Gong, Chao Wang, Ning Wei, Wenhua Liu, Yongqi Wang, Chongxue Zhao, Yaxiong Cui, Defu Hu,