| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862147 | Toxicology in Vitro | 2012 | 8 Pages |
Abstract
⺠CLnA inhibited cell growth of LT-97 more effective than CLA. ⺠Gene expression of FADS1/2, SCD and ELOVL1/5/6 but not ELOVL2 in LT-97 was shown. ⺠This study confirmed conversion of CLnA isomers to CLA isomers in LT-97 cells. ⺠CFA metabolism differed between colon cells: LT-97 (adenoma) and HT-29 (carcinoma). ⺠LT-97 represent a more balanced FA metabolism compared to HT-29.
Keywords
Peptidylprolyl isomerase A (cyclophilin A)HT-29FADS2PPIAFADS1FCSCFASFAMUFAEC50CLACLnAConjugated fatty acidSCD50% effective concentrationArachidonic acidconjugated linolenic acidconjugated linoleic acidFatty acidsaturated fatty acidPolyunsaturated fatty acidmonounsaturated fatty acidPUFAfetal calf serumHuman colon adenocarcinoma cellsFatty acid metabolismFAME یا fatty acid methyl esters
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Authors
Christian Degen, Nina Habermann, Stefanie Piegholdt, Michael Glei, Gerhard Jahreis,