| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862168 | Toxicology in Vitro | 2012 | 9 Pages |
Abstract
⺠Investigate the tissues/gender difference of in vitro CD metabolism in rodents and human. ⺠Demonstrate a probabilistic approach to integrate in vitro information to PBPK models. ⺠Compare the results of estimated metabolism parameters via probabilistic and deterministic method. ⺠Evaluate the impacts of uncertainty of metabolism parameters on the target tissue dosimetry.
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Authors
Yuching Yang, Matthew W. Himmelstein, Harvey J. Clewell,