Article ID Journal Published Year Pages File Type
5862312 Toxicology in Vitro 2012 8 Pages PDF
Abstract
► DEDC showed strong cytotoxicity against neuroblastoma cell line SH-SY5Y. ► Production of intracellular ROS is closely related to apoptosis of SH-SY5Y cells. ► NF-κB inhibitors increased SH-SY5Y cell sensitivity to the pro-apoptotic effect of DEDC. ► The study might offer theoretical basis for treatment of this childhood malignancy.
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Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
DEDC, a new flavonoid induces apoptosis via a ROS-dependent mechanism in human neuroblastoma SH-SY5Y cells
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