Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862319 | Toxicology in Vitro | 2012 | 6 Pages |
Abstract
⺠Abamectin causes hepatotoxicity in animals. ⺠We study the effects of abamectin on the bioenergetics of liver mitochondria. ⺠Abamectin caused dose-dependent inhibition of the mitochondrial ATP synthesis. ⺠Abamectin inhibits the FoF1-ATPase and adenine nucleotide translocator activities. ⺠Impairment of mitochondrial bioenergetics could be involved in abamectin toxicity.
Keywords
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Juliana C. Castanha Zanoli, Marcos A. Maioli, Hyllana C.D. Medeiros, Fábio E. Mingatto,