| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862322 | Toxicology in Vitro | 2012 | 7 Pages |
Abstract
⺠A naringenin derivative N101-2 inhibited the growth of cervical cancer cells, while naringenin itself did not. ⺠N101-2 induces apoptosis via arresting cell cycle at sub-G1 phase. ⺠N101-2 activates mitochondria-emanated intrinsic and Fas/FasL-mediated extrinsic signaling pathways. ⺠N101-2 inhibits PI3K/AKT pathway in human cervical cancer cells.
Keywords
PI3KPBSPARPPVDFPPARDMSOSDS–PAGEsodium dodecyl sulfate–polyacrylamide gel electrophoresisApoptosispolyvinyl difluorideDimethyl sulfoxideCervical cancerPhosphatidyl Inositol 3-kinaseFlavonoidPhosphate-buffered salineNaringeninHuman papillomavirusHPVPropidium iodidepoly ADP-ribose polymeraseperoxisome proliferator-activated receptor
Related Topics
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Health, Toxicology and Mutagenesis
Authors
Jung-Hee Kim, Jeong Woo Kang, Man Sub Kim, Yesol Bak, Yun Sun Park, Kang-Yeoun Jung, Yoong Ho Lim, Do-Young Yoon,