Article ID Journal Published Year Pages File Type
5862324 Toxicology in Vitro 2012 5 Pages PDF
Abstract
► NO2- acted as a reducing agent to remove ferryl heme. ► NO2- exerted pro-oxidant effect on heme-H2O2-induced protein oxidation at lower concentrations. ► NO2- enhanced heme-H2O2-induced loss of HepG2 cell viability dose-dependently. ► NO2- efficiently enhanced the peroxidase activity and oxidative degradation of heme.
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Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
Enhancement of nitrite on heme-induced oxidative reactions: A potential toxicological implication
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