| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862328 | Toxicology in Vitro | 2012 | 8 Pages |
Abstract
⺠Mechanisms of mitochondrial dysfunction during benzo[a]pyrene-induced apoptosis. ⺠GSK3α controls B[a]P-induced c-Myc down-regulation. ⺠c-Myc down-regulation regulates mitochondrial localization of Hexokinase II. ⺠These events are involved in B[a]P-induced intrinsic apoptosis.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
![Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis](/preview/png/5862328.png "First Page Preview: Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis")
Authors
Béatrice Dendelé, Xavier Tekpli, Odile Sergent, Marie-Thérèse Dimanche-Boitrel, Jørn A Holme, Laurence Huc, Dominique Lagadic-Gossmann,