Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862328 | Toxicology in Vitro | 2012 | 8 Pages |
Abstract
⺠Mechanisms of mitochondrial dysfunction during benzo[a]pyrene-induced apoptosis. ⺠GSK3α controls B[a]P-induced c-Myc down-regulation. ⺠c-Myc down-regulation regulates mitochondrial localization of Hexokinase II. ⺠These events are involved in B[a]P-induced intrinsic apoptosis.
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Authors
Béatrice Dendelé, Xavier Tekpli, Odile Sergent, Marie-Thérèse Dimanche-Boitrel, Jørn A Holme, Laurence Huc, Dominique Lagadic-Gossmann,