| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862331 | Toxicology in Vitro | 2012 | 5 Pages |
Abstract
⺠BPA possess estrogenic activity and is one of the most thoroughly studied endocrine disruptors. ⺠Genotoxic and carcinogenic properties of BPA are still not precisely investigated. ⺠Metabolically activated BPA is known to be able to bind DNA. ⺠The chemical reactivity of the bisphenol A-3,4-quinone with deoxyguanosine was calculated. ⺠Michael addition of the deoxyguanosine to bisphenol A-3,4-quinone is essential for genotoxicity.
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Authors
Katra Kolšek, Janez Mavri, Marija Sollner Dolenc,