| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862347 | Toxicology in Vitro | 2012 | 10 Pages |
Abstract
⺠Cd and Ca toxicity were studied using modulators of mitochondrial membrane channels. ⺠The modulators tested reduced mitochondrial uptake of Cd and Ca. ⺠The modulators protected against Cd- and Ca-induced mitochondrial toxicity. ⺠We conclude that mitochondrial membrane channels are involved in Cd and Ca toxicity.
Keywords
VDACRCRFCCPMPTPBKAANTMCUDTTMIBCyclophilin DMRBCyP-DBongkrekic acidmitochondrial permeability transition poreCSAadenine nucleotide translocaseMitochondria respirationRAM, Random Access Memory, Read-Write Memorydithiothreitolruthenium redelectron transport chaincyclosporin ARainbow troutMitochondrial calcium uniporterrespiratory control ratioETcSwellingCadmiumvoltage-dependent anion channelcarbonylcyanide-p-trifluoromethoxyphenylhydrazoneCalcium
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Authors
Reginald C. Adiele, Don Stevens, Collins Kamunde,