Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862356 | Toxicology in Vitro | 2013 | 7 Pages |
Abstract
Our data indicate that sodium butyrate has an effect on AR coregulators expression, transcription activity and histone acetylation in cancer cells, but there is only minimal effect in normal cells. In addition, the results of changes in acetylation level on lysine residues of histone H4 after sodium butyrate treatment confirm its epigenetic effect on prostate cancer cells.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Lenka Paskova, Katerina Smesny Trtkova, Barbora Fialova, Andrea Benedikova, Katerina Langova, Zdenek Kolar,