| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862449 | Toxicology in Vitro | 2013 | 10 Pages |
Abstract
⺠ABA is cytotoxic to rat isolated hepatocytes at concentrations from 25-100 μM. ⺠ABA affects the mitochondrial bioenergetics in rat isolated hepatocytes. ⺠ABA treatment alters intracellular Ca2+ homeostasis. ⺠ABA caused cellular death by necrosis. ⺠Biotransformation of ABA reduces its toxicity.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Marcos A. Maioli, Hyllana C.D. de Medeiros, Marieli Guelfi, Vitor Trinca, Flávia T.V. Pereira, Fábio E. Mingatto,