Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862463 | Toxicology in Vitro | 2013 | 10 Pages |
Abstract
⺠Neu2000 is a novel therapeutic agent for the treatment of central nervous system disorders. ⺠This is the first study to identify the IC50 values of Neu2000 on various free radical species. ⺠Neu2000 strongly scavenged reactive oxygen and nitrogen species (ROS/RNS). ⺠Neu2000 reduced free radicals and oxidative damage in mitochondria. ⺠Neu2000 shows a broad spectrum of antioxidant actions.
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Authors
Nishant P. Visavadiya, Melanie L. McEwen, Jignesh D. Pandya, Patrick G. Sullivan, Byoung Joo Gwag, Joe E. Springer,