| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862483 | Toxicology in Vitro | 2013 | 10 Pages |
Abstract
⺠The oTRP induced inflammatory and genotoxic effects in A549 cells. ⺠NQ contributes to the cytotoxicity and DNA damage. ⺠AQ and NQ participate in inflammation process through inducing different cytokines. ⺠NQ was a more potential inflammatory and genotoxic stressor than AQ.
Keywords
TNFAHRIL-63-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetrazoliumromideFBStBHPNMAIL-8LMAROS formationMCP-1qRT-PCR9,10-AnthraquinoneDMSOMTTROSDNA damagelow melting agaroseinflammationInterleukin-8interleukin-6Dimethyl sulfoxideparticulate matterfetal bovine serumCytokines/chemokinestumor necrosis factorlactate dehydrogenaseLDHtert-butyl hydroperoxidePolycyclic aromatic hydrocarbonsPAHsquantitative real-time polymerase chain reactionMonocyte chemotactic protein-1QuinonesReactive oxygen speciesaromatic hydrocarbon receptor
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Yu Shang, Lanlan Fan, Jialiang Feng, Senlin Lv, Minghong Wu, Bing Li, Yuan-Sheng Zang,