| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862488 | Toxicology in Vitro | 2013 | 6 Pages |
Abstract
⺠Cytotoxicity of indole phytoalexins was studied in human cancer and non-cancer cells. ⺠Significant cytotoxicity was achieved for benzocamalexin (BC) in cancer cells. ⺠It downregulated α, α1 and β5-tubulin expression and caused G2 cell cycle arrest. ⺠BC also induced apoptosis which was accompanied by increasing Bax/Bcl-2 ratio.
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Authors
Martina Pilatova, Lenka Ivanova, Peter Kutschy, Lenka Varinska, Lydia Saxunova, Maria Repovska, Marek Sarissky, Robert Seliga, Ladislav Mirossay, Jan Mojzis,