| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862570 | Toxicology in Vitro | 2011 | 7 Pages |
Abstract
⺠The THTEB is one of the derivatives of tyrosol, which is p-tyrosol combined with gallic acid by an amide bond. ⺠THTEB displayed a significant antiproliferative effect on HeLa cells. ⺠Cell cycle analysis revealed that THTEB could arrest HeLa cells in the S phase. ⺠We found severe DNA damage caused by THTEB by using alkaline single-cell gel electrophoresis.
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![Antiproliferation of HeLa cells by 3,4,5-trihydroxy-N-[2-p-tolylethyl]-benzamide is associated with induction of DNA damage and inhibition of DNA replication](/preview/png/5862570.png "First Page Preview: Antiproliferation of HeLa cells by 3,4,5-trihydroxy-N-[2-p-tolylethyl]-benzamide is associated with induction of DNA damage and inhibition of DNA replication")
Authors
Juan Du, Chunhui Miao, Xin Zhang, In-Hye Jeong, Eun Mi Son, Song You, Burm-Jong Lee, Dong-Kyoo Kim,