| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862663 | Toxicology in Vitro | 2011 | 7 Pages |
Abstract
⺠This study used an IL-1β-provoked inflammation model in primary rat mesangial cells (PRMCs) to resemble glomerulonephritis. ⺠Tetrandrine had no significant effect on viability of PRMCs. ⺠Tetrandrine down-regulated ERK/NF-κB signaling and inhibited the expression of inflammatory mediators NO and MMP-9. ⺠Tetrandrine may play an important role in prevention of glomerulonephritis.
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Authors
Chih-Jen Wu, Yi-Hsuan Wang, Cheng-Jui Lin, Han-Hsiang Chen, Yu-Jen Chen,