Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862730 | Toxicology in Vitro | 2011 | 10 Pages |
Abstract
⺠Octyl and dodecyl gallates were cytotoxic to B16F10 cells in a time dependent manner. ⺠Octyl and dodecyl gallates activated the caspase-3. ⺠Octyl and dodecyl gallates disrupted the mitochondrial potential. ⺠Octyl and dodecyl gallates increased the Bax and decreased Bcl-2 proteins expression. ⺠Octyl and dodecyl gallates induced an oxidative stress in B16F10 cells.
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Authors
Clarissa A.S. de Cordova, Claudriana Locatelli, Laura S. Assunção, Bruno Mattei, Alessandra Mascarello, Evelyn Winter, Ricardo J. Nunes, Rosendo A. Yunes, Tânia B. Creczynski-Pasa,