Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862732 | Toxicology in Vitro | 2011 | 6 Pages |
Abstract
⺠Serotonin is a key neurotransmitter in cognition and mood disorder. ⺠Many animal studies report conflicting results for 5-HT6R ligands. ⺠We investigate effects of 5-HT6R ligands using several in vitro assays. ⺠5-HT6R ligands produce cell toxicity but different cellular effects. ⺠In vitro assays for newly developing chemicals will help interpret in vivo conflicting results.
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Authors
Hyung-Mun Yun, Hyewhon Rhim,