Article ID Journal Published Year Pages File Type
5862732 Toxicology in Vitro 2011 6 Pages PDF
Abstract
► Serotonin is a key neurotransmitter in cognition and mood disorder. ► Many animal studies report conflicting results for 5-HT6R ligands. ► We investigate effects of 5-HT6R ligands using several in vitro assays. ► 5-HT6R ligands produce cell toxicity but different cellular effects. ► In vitro assays for newly developing chemicals will help interpret in vivo conflicting results.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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