Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862799 | Toxicology in Vitro | 2013 | 10 Pages |
Abstract
⺠Nine out 14 tested drugs interfere with TCE metabolism in rat hepatocytes. ⺠Naproxen causes partial competitive inhibition of TCOH glucuronidation.. ⺠Gliclazide and vaproate cause partial non competitive inhibition of TCE oxidation.. ⺠Some inhibition constant values are within range of plasma levels during treatment.
Keywords
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Authors
Mouna Cheikh Rouhou, Isabelle Rheault, Sami Haddad,