Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862800 | Toxicology in Vitro | 2013 | 7 Pages |
Abstract
⺠The anticancererogenic Withaferin A triggers suicidal erythrocyte death (eryptosis). ⺠Withaferin leads to erythrocyte shrinkage and cell membrane scrambling. ⺠Withaferin increases cytosolic Ca2+-activity. ⺠Withaferin stimulated ceramide-formation. ⺠Withaferin thus triggers suicidal death of cells without nuclei and mitochondria.
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Authors
Kashif Jilani, Adrian Lupescu, Mohanad Zbidah, Nazneen Shaik, Florian Lang,