Article ID Journal Published Year Pages File Type
5862800 Toxicology in Vitro 2013 7 Pages PDF
Abstract
► The anticancererogenic Withaferin A triggers suicidal erythrocyte death (eryptosis). ► Withaferin leads to erythrocyte shrinkage and cell membrane scrambling. ► Withaferin increases cytosolic Ca2+-activity. ► Withaferin stimulated ceramide-formation. ► Withaferin thus triggers suicidal death of cells without nuclei and mitochondria.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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