Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862804 | Toxicology in Vitro | 2013 | 11 Pages |
Abstract
⺠DBDCT is a novel diorganotin (IV) compound synthesized by our group. ⺠It showed clear antitumor activity and notable neurotoxicity in vivo. ⺠Mitochondria-mediated apoptosis was responsible for its neurotoxicity. ⺠DBDCT also regulated JNK and p38 signaling pathways in PC12 cells.
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Authors
Rui Ge, Wen-Hua Ma, Yun-Lan Li, Qing-Shan Li,