| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862819 | Toxicology in Vitro | 2013 | 11 Pages |
Abstract
⺠Antiproliferative capacity of Epo A and B in SKOV-3 cells in comparison to PTX were studied. ⺠Epothilones are more cytotoxic than PTX and generate apoptosis mediated by ROS. ⺠Phosphatidylserine externalization and decrease in membrane potential were observed. ⺠Chromatin condensation and apoptotic bodies were noted.
Keywords
NACDCFH2-DAJC-15,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodideHuman ovarian cancer cell lines2′,7′-dichlorodihydrofluorescein diacetate3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideMTTN-acetylcysteineROSSKOV-3EpothilonestaxanesApoptosisCell deathReactive oxygen species
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Authors
Aneta Rogalska, Agnieszka Marczak, Arkadiusz Gajek, Marzena Szwed, Agnieszka ÅliwiÅska, Józef Drzewoski, Zofia Jóźwiak,