Article ID Journal Published Year Pages File Type
5862856 Toxicology in Vitro 2013 8 Pages PDF
Abstract
► Methemoglobin exhibits cytotoxicity towards mouse macrophage cell line J774A.1. ► It causes apoptosis and cellular damage in macrophages. ► Methemoglobin induces multiple ROS spike in cytosol. ► Scavenging ROS by antioxidants give protection against MetHb induced toxicity. ► A potential role of MetHb in macrophage death and tissue damage.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Authors
, ,