Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862894 | Toxicology in Vitro | 2013 | 10 Pages |
Abstract
⺠Normal washing procedures can lead to an incomplete removal of botanical ingredients. ⺠We propose an improvement of the washing procedure for in vitro skin irritation test. ⺠We test 3 new washing procedures for the ability to remove completely sticky/greasy substances. ⺠The SDS 0.1% PBS solution is the most suitable adaptation to ensure an efficient removal. ⺠The SDS 0.1% washing leads to an increase in the predictive ability of the assay.
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Authors
J. Molinari, C. Eskes, E. Andres, N. Remoué, V.M. Sá-Rocha, S.P. Hurtado, C. Barrichello,