| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862927 | Toxicology in Vitro | 2011 | 6 Pages |
Abstract
⺠Pyocyanin generates oxidative stress in A549 cells. ⺠Oxidative stress causally linked to toxicity. ⺠Antioxidant N-acetylcysteine protects against oxidative stress and toxicity suggesting a potential role in therapy. ⺠Oxidative stress may trigger inflammatory responses in pyocyanin by activating NF-κB.
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Authors
Lee S. Gloyne, Gary D. Grant, Anthony V. Perkins, Katie L. Powell, Catherine M. McDermott, Peter V. Johnson, Gregory J. Anderson, Milton Kiefel, Shailendra Anoopkumar-Dukie,