Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862931 | Toxicology in Vitro | 2011 | 7 Pages |
Abstract
⺠Luteolin induced apoptosis on A549 cells through a mitochondria-dependent apoptosis passway. ⺠Luteolin induced apoptosis via both IκBα/NF-κB signal passway and JNK passway. ⺠Luteolin could inhibit TNFα induced NF-κB translocation on A549 cells. ⺠Luteolin caused G2 phase cell cycle arrest on A549 by inhibition the expression of cyclin A and phosphorylation of CDC2.
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Authors
Xueting Cai, Tingmei Ye, Chao Liu, Wuguang Lu, Min Lu, Juan Zhang, Min Wang, Peng Cao,