Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862940 | Toxicology in Vitro | 2011 | 11 Pages |
Abstract
⺠Whole cell and cytoplasm mRNA levels are poor predictors of polysome mRNA levels. ⺠mRNA levels are regulated independently in the nucleus, cytoplasm, and polysomes. ⺠A large proportion of polysome mRNAs exit the nucleus for immediate polysome entry. ⺠Polysome mRNA profiling generated new genes and pathways related to TCDD toxicity.
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Authors
Jessica A. Thornley, Heidi W. Trask, Christian J.A. Ridley, Murray Korc, Jiang Gui, Carol S. Ringelberg, Sinny Wang, Craig R. Tomlinson,