| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862965 | Toxicology in Vitro | 2012 | 6 Pages |
Abstract
⺠We established a series of defective human bronchial epithelial cell (HBE) models in DNA repair gene. ⺠The defective HBE cell models were more sensitive in BaP-induced DNA damages. ⺠The suppression of DNA repair gene could not shorten the latency of BaP-induced cell transformation. ⺠Silencing of a single DNA repair gene does not confer cells susceptible to chemical-induced cell transformation.
Keywords
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Health, Toxicology and Mutagenesis
Authors
Xiumei Xing, Caixia Liu, Shifu Tang, Daochuan Li, Liping Chen, Yaqin Pang, Qing Wang, Bo Zhang, Xiaowen Zeng, Wen Chen, Yongmei Xiao,