Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5862966 | Toxicology in Vitro | 2012 | 10 Pages |
Abstract
⺠3â²-Nitro-3-phenylamino nor-β-lapachone (QPhNO2) is more active than its precursor. ⺠QPhNO2 suffers auto-oxidation and is DNA-reactive. ⺠QPhNO2 induces apoptosis of HL-60 cells via a redox-dependent mechanism.
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Authors
A.J. Araújo, A.A. de Souza, E.N. da Silva Júnior, J.D.B. Marinho-Filho, M.A.B.F. de Moura, D.D. Rocha, M.C. Vasconcellos, C.O. Costa, C. Pessoa, M.O. de Moraes, V.F. Ferreira, F.C. de Abreu, A.V. Pinto, R.C. Montenegro, L.V. Costa-Lotufo,