Article ID Journal Published Year Pages File Type
5862983 Toxicology in Vitro 2012 6 Pages PDF
Abstract
► The imidazolium-based ionic liquid (IL) has cytotoxicity on PC12 cells. ► The IL causes DNA damage and apoptosis in PC 12 cells. ► The IL induces rise of intracellular Ca2+, overproduction of ROS, and exhausted ATP. ► The IL induce mitochondrial permeability transition in the cells.
Keywords
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
Toxic cytological alteration and mitochondrial dysfunction in PC12 cells induced by 1-octyl-3-methylimidazolium chloride
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