Article ID Journal Published Year Pages File Type
5862989 Toxicology in Vitro 2012 8 Pages PDF
Abstract
► T-2 Toxin enhanced catabolic gene expression in hypertrophic chondrocytes. ► HIF-2α was a crucial mediator in T-2 toxin treatment. ► T-2 Toxin induced the degradation of IκB-α and the production of ROS. ► We confirmed that ROS-NF-κB-HIF-2α pathway participated in the process.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Authors
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