| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5862995 | Toxicology in Vitro | 2012 | 8 Pages |
Abstract
⺠Effects of p33-NP, p262-NP, p353-NP and p363-NP on steroidogenesis were tested. ⺠NP isomers showed varying degrees of inhibition of testosterone biosynthesis. ⺠p363-NP led to the most significant decrease in testosterone level. ⺠NP isomers down regulated Hsd3b, Cyp11a1 and Star expression to various extent. ⺠NP isomers induced enhancement of Leydig cell apoptosis in various degrees.
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Authors
Feng Ying, Chao Ding, Rong Ge, Xueting Wang, Fangjie Li, Yangheng Zhang, Qiuqiong Zeng, Bin Yu, Rong Ji, Xiaodong Han,