Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5863013 | Toxicology in Vitro | 2012 | 9 Pages |
Abstract
⺠We showed in vitro cytotoxicity of lectins on leukemic and mononuclear cells. ⺠The index of DNA damage was measured using comet assay. ⺠Changes in cell morphology were determined by fluorescence microscopy. ⺠Apoptosis induction and cell cycle were demonstrated by flow cytometry. ⺠Lectins induced cell death by collapse of mitochondrial potential.
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Authors
Glaucia V. Faheina-Martins, Alethéia Lacerda da Silveira, Bruno C. Cavalcanti, Márcio V. Ramos, Manoel O. Moraes, Cláudia Pessoa, Demetrius A.M. Araújo,