Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5863051 | Toxicology in Vitro | 2012 | 9 Pages |
Abstract
⺠Classification of NSAIDs in three classes based on underlying toxicity. ⺠Ketoprofen and indomethacin show same mitochondrial toxicity as diclofenac. ⺠Main toxicity ibuprofen and naproxen is not related to mitochondrial respiration. ⺠Use of yeast as a simple, cellular model system to test toxicity.
Keywords
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Authors
Jolanda S. van Leeuwen, Betül Ãnlü, Nico P.E. Vermeulen, J. Chris Vos,