| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5863072 | Toxicology in Vitro | 2012 | 9 Pages |
Abstract
⺠We determined ROS, MAPKs activation, and Egr-1 and IL-6 upregulation in endothelial cells with exposure to UFPs and/or CSE. ⺠ROS generation in cells exposed to UFPs and/or CSE activated MAPKs induced Egr-1 upregulation and IL-6 generation. ⺠Coexposure to UFPs with CSE greatly enhanced these effects, resulting in endothelial inflammation and dysfunction.
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Authors
Yiqun Mo, Rong Wan, Lingfang Feng, Sufan Chien, David J. Tollerud, Qunwei Zhang,