| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5863088 | Toxicology in Vitro | 2012 | 11 Pages |
Abstract
⺠Human amniotic (WISH) cells exposed to TiO2-NPs demonstrated cytotoxic response. ⺠TiO2-NPs treated cells exhibited decline in catalase and glutathione enzymes. ⺠The treated cells show a significant increase in intracellular ROS generation. ⺠TiO2-NPs treated cells also demonstrated the formation of DNA double strand breaks. ⺠With increasing concentration of TiO2-NPs, WISH cells showed G2/M cell cycle arrest.
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Authors
Quaiser Saquib, Abdulaziz A. Al-Khedhairy, Maqsood A. Siddiqui, Faisal M. Abou-Tarboush, Ameer Azam, Javed Musarrat,