Using a randomised controlled trial (RCT) methodology in CAM research with gynaecological cancer patients: A commentary on the perks and pitfalls

This paper provides a commentary on several challenges faced by researchers when conducting randomised controlled trials (RCTs) utilising complementary therapies with cancer patients. Several factors, such as research design and recruitment to the intervention are discussed. Examples are drawn from an RCT conducted by the lead author regarding the use of yoga to improve the quality of life of gynaecological cancer patients undergoing treatment for their cancer. This paper gives methodological insights into some of the difficulties experienced when conducting research with cancer patients, and provides a number of recommendations based on the available evidence and practical application of these methods.