| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5865538 | Complementary Therapies in Medicine | 2014 | 7 Pages |
Abstract
Our research demonstrated that Chinese medicine formula FTZ has multi-target synergistic effect on hyperlipidemia and suggests the pharmacodynamic material basis could be jatrorrhizine, berberrubine, berberine and salidroside.
Keywords
SARRhizoma CoptidisSQSoxidosqualene cyclaseLXRFXRPolypharmacologyPPARMMFFLDL-CTCMHMGRMerck Molecular Force FieldHDLOSCCETPfarnesoid X receptorHMG-CoA reductaseUPLC/Q-TOF-MSsqualene synthaseStructure–activity relationshipRSMtraditional Chinese medicineVirtual screeninghigh density lipoproteinHyperlipidemiacholesteryl ester transfer proteinMolecular dockingliver X receptortotal cholesterolTotal triglyceridelow density lipoprotein cholesterolPeroxisome proliferator-activated receptors
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Authors
Laiyou Wang, Weiye Tao, Duosheng Luo, Yinming Hu, Weijian Bei, Jiao Guo,