Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5871648 | Clinical Nutrition | 2011 | 9 Pages |
Abstract
Key proteins implicated in taste signaling are present in the human gut and co-localized with GLP-1 suggesting that these proteins are functionally linked to peptide secretion from enteroendocrine cells. Glucose-stimulated secretion of GLP-1 and PYY is reduced by a sweet taste antagonist, suggesting the functional involvement of gut-expressed sweet taste receptors in glucose-stimulated secretion of both peptides in humans.
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Authors
R.E. Steinert, A.C. Gerspach, H. Gutmann, L. Asarian, J. Drewe, C. Beglinger,