Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5873317 | Journal of Stroke and Cerebrovascular Diseases | 2014 | 7 Pages |
Abstract
Our results demonstrate the feasibility of fast, efficient, and safe thrombolysis in an in vivo porcine model of ICH and in 2 ex vivo models using a human skull, without introducing tPA. Future studies will further optimize parameters and assess the nature of sonication-mediated versus natural clot lysis, the risk of rebleeding, the potential effect on the adjacent parenchyma, and the chemical and toxicity profiles of resulting lysate particles.
Keywords
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Authors
Sagi MD, Zion MD, Arik MD, Stephen MD, Javier BSc, Gilat BSc, Iris PhD, Neal MD,